2nd Edition of Preventive Medicine World Conference 2026

Abstract

Background: Breast cancer is a significant public health issue in Ethiopia, with rising incidence rates and unique survival dynamics. This study aims to evaluate the impact of Chemotherapy response   and diet diversity on Survival status among   Ethiopian Breast cancer patients.

Methods: A multicenter prospective cohort study design was conducted, involving 120 newly diagnosed breast cancer patients who received chemotherapy treatment from April 2024 to Septemberb2025. A structured questionnaire, checklist, 24-hours recall 10-food items questionnaire, and anthropometric measurements were used for data collection. The data were cleaned and analyzed using   R software. Descriptive and inferential statistics were employed.

Results: Response rates were 85.8% at the first follow-up and 79.2% at the second follow-up period. Participants had a mean age of 41.7 years. The median   follow-up duration since diagnosis was 7.0 months. At baseline, 2.7% of patient’s medical records had a family history, 37.5% were stage III, and 73.3% had metastasis. 32.5%, 58.3%, and 69.5% had adequate dietary diversity scores at baseline, first follow-up, and the second follow-up, respectively. Chemotherapy treatments decreased from 84.2% to 77.5%, while chemotherapy combined with surgery rose from 61.7% to 67.5%.

The result of the Friedman test indicated a significant change in diet diversity scores χ2= 26.6, p=0.00, body mass index χ2=10.8, p=0.004, tumor size χ2=30.4, p=0.00, progesterone expression χ2= 98.9, p=0.00, and Estrogen receptor χ2=9.5, p=0.009. The result of Kaplan-Meier Survival analysis revealed that diet diversity score and tumor size had   significant on the survival status of the breast cancer patients with p< 0.05.

Conclusion: This study demonstrates a significant association between chemotherapy response and dietary diversity among Ethiopian breast cancer patients. Combined treatment modalities showed favorable trends. These initial findings highlight the importance of integrating nutritional considerations into breast cancer management strategies.